TFF1 anticorps

N° du produit ABIN6945144

Cet anticorps Lapin Monoclonal détecte spécifiquement TFF1 dans FACS, IHC (p), IF (cc) et IF (p). Il présente une réactivité envers Humain.

Aperçu rapide pour TFF1 anticorps (ABIN6945144)

Antigène: TFF1 (Trefoil Factor 1 (TFF1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp TFF1 est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Clone: 4B1

Détail du produit anti-TFF1 anticorps

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: Synthetic peptide within human TFF1 aa 50-100

Isotype: IgG

Information d'application

Indications d'application: FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 12 months

Détails sur TFF1

Antigène: TFF1 (Trefoil Factor 1 (TFF1))

Autre désignation: TFF1

Sujet:

Synonyms: Trefoil factor 1, Breast cancer estrogen-inducible protein, PNR-2, Polypeptide P1 A, Protein pS2, hP1 A, BCEI, PS2, TFF1, Estrogen Inducible Protein pS2.

Background: Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. TFF1 has been found to be a stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. TFF1 may inhibit the growth of calcium oxalate crystals in urine.

ID gène: 7031

UniProt: P04155

Pathways: EGFR Signaling Pathway